Localized sarcoidosis in an old tattoo: Illustrating the principle of locus minoris resistentiae
Case-Based review, 111 - 114Tag this article
Cutaneous manifestations of sarcoidosis are common but varied in clinical presentation. We present a case of a patient with history of systemic sarcoidosis who presented with firm papules within multiple old tattoos. Pathology of one lesion revealed granulomatous infiltration consistent with sarcoidosis within an old tattoo. The patient was also found to have erythema nodosum, hilar lymphadenopathy, and arthralgias, and was diagnosed with Lofgren syndrome. This case of cutaneous sarcoid manifesting in an old tattoo illustrates the principle of locus minoris resistentiae (LMR). We review the pathophysiology of LMR, including the concept of the immunocompromised cutaneous district and cutaneous mosaicism.
KEY WORDS: sarcoidosis; tattoo; locus minoris resistentiae.