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Clinical Dermatology

Atrophoderma following the lines of Blaschko: an interesting diagnostic dilemma. Linear Atrophoderma of Moulin, blaschkolinear Atrophoderma of Pasini and Pierini or linear morphea?

Case-based review, 29 - 36
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Abstract
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Dermatoses that may present in a linear distribution and with quite similar histological findings include linear atrophoderma of Moulin (LAM), atrophoderma of Pasini and Pierini (APP) and linear morphea. We present
a review of the literature and two new cases that could be diagnosed as LAM, one of which is the oldest one ever described while the other has an ususual bilateral localization. The distribution along Blaschko’s lines (BL) was a characteristic of LAM, but
some cases have been later redefined as blaschkolinear APP or morphea following the BL. In fact, even though Moulin et al. described biopsy specimens with just a basal hyperpigmentation overlying an unaltered dermis, some published cases of LAM present
different histological findings but have been classified under the same umbrella. Whether or not our patients represent a genuine form of LAM will depend on how willing we are to expand the definition of LAM. We suggest that the too subtle and overlapping histopathological findings of a single biopsy specimen could just reflect different stages of the spectrum of an evolving dermatosis. Thus, a long followup with repeated biopsies should be performed in order to reach the correct definitive diagnosis.

Vol. 6 (No. 1-2) 2018 January - June

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