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Clinical Dermatology

Systemic immunosuppressive treatment in adult patients with atopic dermatitis: current and new treatment options

Review, 22 - 29
doi: 10.11138/cderm/2017.5.1.022
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Abstract
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Treatment options for severe, difficult to treat atopic dermatitis patients are currently limited. Cyclosporine
A is registered for the treatment of atopic dermatitis in many European countries. Alternative off-label treatment options are azathioprine, mycophenolate sodium and methotrexate. Dupilumab® is the first biologic, which is extensively studied in atopic dermatitis.
Several other systemic immunosuppressive/immunomodulatory drugs for treatment of moderate to severe atopic dermatitis, including small molecules and other monoclonal antibodies (anti-IL13 and anti-IL31), are currently studied in clinical trials.

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  1. Systemic immunosuppressive treatment in adult patients with atopic dermatitis: current and new treatment options
    van der Schaft J., Thijs J.L., Hijnen D., de Bruin-Weller M.S.
    doi: 10.11138/cderm/2017.5.1.022
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